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Episode 1 Andy Kindler, motocross demo with Travis Pastrana, Baby Gramps
Episode 2 Zach Braff, Jeff Brendenburg, The Roots
Episode 3 Snoop Dogg, Charlie Hill, OK Go
Episode 4 Julianne Moore, radio-show hosts Opie and Anthony
Episode 5 Al Franken, Todd Snider
Episode 6 Maria Sharapova, Martha Stewart, Justin Timberlake
Episode 7 Ashton Kutcher, Sam Hornish, Jr., TV on the Radio
Episode 8 Dwayne "The Rock" Johnson, Norm MacDonald
Episode 9 Anne Heche, Luke Ravenstahl, The Who
Episode 10 Johnny Knoxville, Rachael Ray
Episode 11 Dr. Phil McGraw, Willie Tyler and Lester, Sekou Bunch
Episode 12 Patrick Dempsey, Jay Johnson and Darwin, Kasabian
Episode 13 Marg Helgenberger, Ronn Lucas and Scorch, Diana Krall
Episode 14 Ted Turner, Jeff Dunham and Walter, Fergie
Episode 15 LeBron James, Todd Oliver and Irving, Ludacris
Episode 16 Ray Liotta, Elvis Costello & Tony Bennett, Billy Garcia
Episode 17 Billy Bob Thornton, Lily Capehart, Sean Lennon
Episode 18 Amanda Peet, Nigella Lawson, Bob Seger
Episode 19 Sir Richard Branson, Dane Cook, Monica
Episode 20 Nathan Lane, Jeff Caldwell
Episode 21 Pete Rose, Roy Wood Jr., Cecilia Mansilla
Episode 22 Andy Dick, Keith Olbermann, Brazilian Girls
Episode 23 Alec Baldwin, Vladae the Dog Wizard, Jerry Lee Lewis & Neil Young
Episode 24 Frank Caliendo, Rachael Harris, Xzibit, Phil Pfister
Episode 25 Amy Sedaris, Trey Anastasio
Episode 26 Robin Williams, J.P. Calderon, Sam Moore with Wynonna
Episode 27 Nicky Hilton, Bob Woodward, Joseph Arthur
Episode 28 Jon Stewart, Nick Lachey
Episode 29 Katie Couric, Brian Kiley, Alan Jackson
Episode 30 Diddy, Neil Patrick Harris
Episode 31 Tom Arnold, Brian Regan, the latest "Survivor: Cook Islands" castaway
Episode 32 Tina Fey, Mike Golic & Mike Greenberg, The Killers
Episode 33 Julia Louis-Dreyfus, Jay Thomas, John Legend
Episode 34 Tim Robbins, Gene Rurka, Russell Thompkins Jr. and The New Stylistics
Episode 35 Bill O'Reilly, Jeff Altman, Tilly and the Wall
Episode 36 Borat, Tiki Barber, Beck
Episode 37 Rachel Weisz, David Rakoff, Morningwood
Episode 38 Gary Sinise, Joanne Carson, Jim Norton
Episode 39 Rosie O'Donnell, Lady Sovereign
Episode 40 Martin Short, Kinky Friedman
Episode 41 Will Ferrell, Jack Hanna
Episode 42 Dustin Hoffman, Jamie Oliver, The Metropolitan Opera
Episode 43 Kiefer Sutherland, Jenna Fischer, Rocco DeLuca
Episode 44 Daniel Craig, documentary film subject Teri Horton, Elvis Costello, Rosanne Cash
Episode 45 Robin Williams, Rich Little, George Jones
Episode 46 Jack Black & Kyle Gass, Fred Travalena, Tenacious D
Episode 47 Ellen DeGeneres, Gordie Brown, +44
Episode 48 Christopher Guest, Frank Caliendo, The Game
Episode 49 Sen. John Edwards, Kevin Pollak, Will Arnett
Episode 50 Jerry Seinfeld, Dan Patrick
Episode 51 Hugh Jackman, Chris Elliott, Jimmie Johnson
Episode 52 Matthew Broderick, Lupe Fiasco & Jill Scott
Episode 53 Eugene Levy, John Mayer
Episode 54 Helen Hunt, DJ Shadow, Q-Tip and Lateef
Episode 55 Kate Winslet, Tom Waits
Episode 56 George Clooney, The Decemberists
Episode 57 Richard Simmons, Kate Walsh, Ciara
Episode 58 Jennifer Connelly, Tom Dreesen, Shiny Toy Guns
Episode 59 Danny DeVito, 16-year-old duct tape expert William Beacom, Silversun Pickups
Episode 60 Matt Damon, Barbara Walters
Episode 61 Howard Stern, Gwen Stefani
Episode 62 Kid Scientists, Regis Philbin, Robert Randolph
Episode 63 Will Smith, Evanescence
Episode 64 Clint Eastwood, Matthew Fox
Episode 65 Frank Caliendo as John Madden, Ben Stiller, Rodrigo & Gabriela
Episode 66 Beyonce, Marv Albert, The Dears
Episode 67 Renée Zellweger, holiday toy demonstration, Taking Back Sunday
Episode 68 Tom Brokaw, Cold War Kids
Episode 69 Cate Blanchett, Jay Thomas, Darlene Love
Episode 70 Martin Short, Donal Logue
Episode 71 Matt Lauer, Artie Lange, Augustana
Episode 72 Cedric the Entertainer, Wesley Autrey, Switchfoot
Episode 73 Donald Trump, Mary Lynn Rajskub
Episode 74 David Arquette, Jennifer Hudson
Episode 75 Penelope Cruz, Gary Mule Deer, Ben E. King
Episode 76 Peter O'Toole, Marc Maron
Episode 77 Julianne Moore, Madonna, The Hold Steady
Episode 78 Kristin Chenoweth, John Witherspoon, Josh Ritter
Episode 79 Amy Sedaris, Jason Randal, America with Ryan Adams & Ben Kweller
Episode 80 Paul Newman, Sebastian Bourdais, Diana Ross
Episode 81 Tina Fey, Terri and Bindi Irwin
Episode 82 Harry Shearer, Vera Farmiga, Mat Kearney
Episode 83 Dan Rather, Tricia Helfer, Andy Kindler
Episode 84 Kevin Spacey, Alicia Keys, Nellie McKay & The Brooklyn Philharmonic
Episode 85 Ricky Gervais, Forest Whitaker, The Shins
Episode 86 Frank Caliendo, Mandy Moore, Rosanne Cash
Episode 87 Bill Murray, LeBron James
Episode 88 David Spade, Alexandra Pelosi, Dustin Kensrue
Episode 89 Dr. Phil McGraw, Fall Out Boy
Episode 90 Randy Jackson, Harry Connick Jr., Regis
Episode 91 Chris Elliott, Kelly Ripa, John Mellencamp
Episode 92 Jack Hanna, Katherine Heigl, Patty Griffin
Episode 93 Rachael Ray, Frank Caliendo, The Fab Faux
Episode 94 Drew Barrymore, Rickie Lee Jones, Kevin Johnson with Clyde & Matilda
Episode 95 Peyton Manning, Dan Horn with Orson, The Cat Empire
Episode 96 Martha Stewart, Otto Petersen with George, Norah Jones
Episode 97 Sienna Miller, NAS, Jim Barber with Seville
Episode 98 Tracy Morgan, Gabrielle Union, Brad Cummings and Rex
Episode 99 Jim Carrey, Daytona 500 winner Kevin Harvick
Episode 100 Barbara Walters, David Neeleman, K-os
Episode 101 John Travolta, Eric Nerhus, a performance from the Broadway musical "Spring Awakening"
Episode 102 Billy Bob Thornton, Rashida Jones, Barenaked Ladies
Episode 103 Samuel L. Jackson, Jim Gaffigan
Episode 104 Jake Gyllenhaal, Brand New
Episode 105 Evangeline Lilly, Jeff MacGregor, bubble blowing guy Tom Noddy
Episode 106 Sen. John McCain, Robin Thicke
Episode 107 Bob Woodruff, John Mayer
Episode 108 Charles Grodin, Dan Naturman
Episode 109 Chris Rock, Sandra Oh, Amy Winehouse
Episode 110 Jeff Goldblum, Barbara McQueen
Episode 111 Richard Gere, Explorers Club chef Gene Rurka, Aqualung
Episode 112 Bernie Mac, Paula Abdul, Joss Stone
Episode 113 Adam Sandler, Don Cheadle, Danica Patrick, Todd Barry, Lucinda Williams
Episode 114 Jack Black, Lara Logan, beer launching refrigerator creator John Cornwell
Episode 115 Will Ferrell, Kings of Leon, Rachel Smith
Episode 116 Patricia Arquette, Paul Mooney, Macy Gray
Episode 117 Al Franken, Isla Fisher
Episode 118 Rosario Dawson, Bloc Party, Piedmont bird callers
Episode 119 Donald Trump, Jon Heder
Episode 120 Sen. Barack Obama, Halle Berry, Zach Johnson
Episode 121 David Duchovny, Ryan Howard, Andrew Bird
Episode 122 Alec Baldwin, Debbie Parkhurst and her dog Toby, LCD Soundsystem
Episode 123 Bruce Willis, Jason Randal
Episode 124 Bill Cosby, Angela Kinsey
Episode 125 Kelly Ripa, Simon Pegg
Episode 126 Craig Ferguson, Dave Della Terza, Avril Lavigne
Episode 127 Edie Falco, Paul Scheer, Son Volt
Episode 128 Garry Shandling, Paul Teutul Sr. and Jr., Tokyo Police Club
Episode 129 Jessica Biel, Ira Glass, Regina Spektor
Episode 130 Brian Williams, Steven Wright, a Top Ten list presented by Sanjaya Malakar
Episode 131 David Hyde Pierce, Ivanka Trump, Corinne Bailey Rae
Episode 132 Nicolas Cage, Barry Sonnenfeld, The Fratellis
Episode 133 Steve Martin, Dave Cota and A.J. the parakeet, Derek Jeter
Episode 134 Frank Caliendo as President George W. Bush, Andy Dick, Jarvis Cocker
Episode 135 Kirsten Dunst, Rob Magnotti, Dinosaur Jr.
Episode 136 Tobey Maguire, John Byner, Modest Mouse
Episode 137 Drew Barrymore, Mike MacRae, Ben Kweller
Episode 138 Marcia Cross, Joe Piscopo, Tori Amos
Episode 139 Ray Romano, Reggie Reg, Dennis Haysbert
Episode 140 Regis Philbin, Darlene Love
Episode 141 Jane Fonda, Tom Ruprecht, Kelly Clarkson
Episode 142 Lindsay Lohan, Tom Dreesen, The Kooks
Episode 143 Dr. Phil McGraw, Jack Hanna
Episode 144 Charles Grodin, Jake Johannsen
Episode 145 Mike Myers, America Ferrera
Episode 146 Don Rickles, Michael Imperioli, Wilco, a Top Ten List presented by Masi Oka
Episode 147 Ricky Gervais, Mary Lynn Rajskub, Mavis Staples, a Top Ten List presented by Bob Barker
Episode 148 Kid Scientists, Luke Wilson, Rufus Wainwright, a Top Ten List presented by Homer Simpson
Episode 149 Teri Hatcher, Jonah Hill, Elvis Costello
Episode 150 Rudolph Giuliani, Mike West, Jesus & Mary Chain
Episode 151 Charles Barkley, Seth Rogen, Michael Martin Murphey
Episode 152 Stupid Pet Tricks, Rosie Perez, Dr. Dog
Episode 153 Al Gore, Jim Short
Episode 154 Kevin Spacey, Alexis Bledel
Episode 155 Matt Damon, Indianapolis 500 winner Dario Franchitti, Bright Eyes
Episode 156 Chevy Chase, Amanda Beard, Satellite Party
Episode 157 Nicole Richie, Artie Lange, Chrisette Michele
Episode 158 Amy Sedaris, Chuck "The Iceman" Liddell, Jordan Zevon
Episode 159 Ellen Barkin, Brian Regan
Episode 160 Denis Leary, Flight of the Conchords, Neal Seaver
Episode 161 Kyra Sedgwick, Sir Richard Branson, Maroon 5
Episode 162 Bear Grylls, Jeremy Piven, Elvis Perkins
Episode 163 John Cusack, Pink Martini, Turkey Gobbling Champions
Episode 164 Michael Moore, Bill Burr
Episode 165 Bruce Willis, Tony Parker, diving dogs
Episode 166 Amanda Peet, John Krasinski, Bryan Ferry
Episode 167 Claire Danes, Dan Patrick & Keith Olbermann, Ryan Adams & The Cardinals
Episode 168 Robin Williams, Julie Chen
Episode 169 Dennis Kucinich, Shia LaBeouf, Morrissey
Episode 170 Don Cheadle, Smashing Pumpkins, Venus Williams
Episode 171 Sienna Miller, Michael Cera, Interpol
Episode 172 Diddy, Emma Watson, Spoon
Episode 173 Paul Teutul Sr. and Jr., Vera Farmiga, Joe Matarese
Episode 174 Queen Latifah, Alan Zweibel, Smashing Pumpkins
Episode 175 Michelle Pfeiffer, Jonah Hill, Michel Lauziere
Episode 176 Adam Sandler, Mike Golic and Mike Greenberg, Mute Math
Episode 177 John Travolta, Paula Abdul, Teddy Thompson
Episode 178 Kevin James, Jose Andres, White Rabbits
Episode 179 Julia Stiles, Pete Jordan, Nick Griffin
Episode 180 Drew Carey, Nikki Blonsky, Grinderman
Episode 181 Paul Rudd, Tony Dungy, The National
Episode 182 Catherine Zeta-Jones, Bob Sarlatte, Porter Wagoner
Episode 183 Sharon Osbourne, Brian Kiley, Yeah Yeah Yeahs
Episode 184 Anne Hathaway, Jim Gaffigan, Buffalo Tom
Episode 185 Andy Samberg, Catherine Bell, The Bravery
Episode 186 Sen. Joe Biden, Seth Rogen, Gogol Bordello
Episode 187 Matt Damon, Jeff Altman, Angelique Kidjo
Episode 188 Jackie Chan, Chelsea Handler, Michael Buble
Episode 189 Glenn Close, Judd Apatow, Chris & Rich Robinson
Episode 190 Jeff Goldblum, Hayden Panettiere, New Pornographers
Episode 191 Samuel L. Jackson, Christiane Amanpour, Tom Russell
Episode 192 Richard Gere, Tom Dreesen, Velvet Revolver
Episode 193 Tina Fey, Venus Williams, Steve Earle
Episode 194 Tom Arnold, Kristin Gore, Jim McDonald
Episode 195 Susan Sarandon, Rick Reilly, Feist
Episode 196 Kevin Bacon, Kat Von D, T.I. with Wyclef
Episode 197 Ellen DeGeneres, Jeff Garlin, Against Me!
Episode 198 Sen. Hillary Rodham Clinton, Willie Nelson & Kenny Chesney
Episode 199 Amy Sedaris, Will Arnett
Late Show with David Letterman - Season 14 Episode 41 : Will Ferrell, Jack Hanna
Britney Spears drops by looking for Will Ferrell; at the end of his interview, Will ad-libs through a selection from "Phantom of the Opera"; Jack Hanna introduces Dave to Fluffy the python, the largest-known snake in captivity.
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