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Episode 1 Nicolas Cage, Anna Torv, Terrence Howard
Episode 2 Dr. Phil McGraw, Tilda Swinton, Tricky
Episode 3 Robin Williams, Shannen Doherty, Duffy
Episode 4 John Malkovich, Hayden Panettiere, Steve Earle
Episode 5 Keira Knightley, Thomas L. Friedman
Episode 6 Jada Pinkett Smith, Chris Russo, Michael Buble
Episode 7 Sen. Barack Obama, LeBron James
Episode 8 Jessica Simpson, Jack Hanna
Episode 9 Meg Ryan, Ricky Gervais
Episode 10 Bill Clinton, Chris Rock
Episode 11 Julianne Moore, Tom Dreesen & Tim Reid, Kings of Leon
Episode 12 Keith Olbermann, Chandra Wilson, Delta Goodrem
Episode 13 Paris Hilton, Usain Bolt, Morningwood
Episode 14 Lance Armstrong, Kristen Wiig, TV on the Radio
Episode 15 Julia Louis-Dreyfus, Michael Cera, Pete Seeger
Episode 16 Anne Hathaway, Josette Sheeran, The Virgins
Episode 17 Kate Walsh, Barry Sonnenfeld, Darius Rucker
Episode 18 Calista Flockhart, Bill Hader, Lucinda Williams
Episode 19 Brian Williams, Tim Robbins
Episode 20 Russell Crowe, Sarah Vowell, The Pretenders
Episode 21 Debra Messing, John Carter, Tegan & Sara
Episode 22 Dennis Quaid, Sarah Chalke, Buddy Guy
Episode 23 Bill Murray, Beck
Episode 24 Jeremy Piven, Elizabeth Banks, Lou Reed
Episode 25 Sarah Silverman, the Teutuls, Ra Ra Riot
Episode 26 Josh Brolin, Amy Sedaris, Blues Traveler
Episode 27 Martin Short, Marv Albert
Episode 28 Sen. John McCain, Ne-Yo
Episode 29 Tina Fey, Frank Caliendo, Tim Montana
Episode 30 Bill O'Reilly, Lauren Conrad
Episode 31 Regis Philbin, James Taylor
Episode 32 Alec Baldwin, Paul Mooney, Ryan Adams
Episode 33 Ashley Olsen, Paul Rudd, John Legend
Episode 34 Marcia Cross, Alan Zweibel
Episode 35 Paris Hilton, Elvis Costello, Jenny Lewis, a Top Ten List by Ricky Gervais
Episode 36 Tom Brokaw, Vera Farmiga
Episode 37 Ben Stiller, Q-Tip
Episode 38 Natalie Portman, Artie Lange, Brad Paisley
Episode 39 Ted Turner, Jamie Oliver, Taylor Swift
Episode 40 Don Rickles, Amy Brenneman, Alicia Keys
Episode 41 Russell Brand, Charlie Haden
Episode 42 Bruce Willis, Sia
Episode 43 Bill Cosby, Matt Braunger
Episode 44 Emma Thompson, Michelle Felicetta, Purple Reign
Episode 45 Carla Bruni Sarkozy, Jack Hanna, Cold Hard Cash
Episode 46 Katie Couric, Dev Patel, Mr. Brownstone
Episode 47 Stephen Colbert, Kristen Stewart, Super Diamond
Episode 48 James Franco, Bruce McCall, The Allstarz
Episode 49 Nicole Kidman, Simon Baker, Kanye West
Episode 50 Reese Witherspoon, Harry Connick Jr.
Episode 51 Teri Hatcher, Ludacris
Episode 52 Denis Leary, John Mayer
Episode 53 Tom Arnold, Faith Hill
Episode 54 Jennifer Connelly, Anderson Cooper, The Duke Spirit
Episode 55 Amy Adams, Michael Sheen, Jamey Johnson
Episode 56 Keanu Reeves, Paula Abdul, Loudon Wainwright III
Episode 57 Sen. John McCain, Bon Iver
Episode 58 Meryl Streep, Jeff Altman
Episode 59 Adam Sandler
Episode 60 Tom Cruise, Fall Out Boy
Episode 61 Jennifer Aniston, Broken Social Scene
Episode 62 Will Smith, Of Montreal
Episode 63 Jerry Seinfeld, Leona Lewis
Episode 64 Dustin Hoffman, Todd Rundgren
Episode 65 Jay Thomas, Mickey Rourke, Darlene Love
Episode 66 Tracy Morgan, Matt Braunger
Episode 67 Kate Hudson, Glasvegas
Episode 68 Kevin James, Becky Quick, Erin McCarley
Episode 69 Ricky Gervais, Rose Byrne, Okkervil River
Episode 70 Kate Winslet, Marv Albert
Episode 71 Kiefer Sutherland, Wendy Liebman
Episode 72 Billy Crystal, Kara DioGuardi
Episode 73 Salma Hayek, Jimmie Walker
Episode 74 Clint Eastwood, Randy Rogers Band
Episode 75 Kyra Sedgwick, Gwen Ifill
Episode 76 Zach Braff, Arj Barker, The Airborne Toxic Event
Episode 77 Brian Williams, Ben Kweller
Episode 78 Evangeline Lilly, Seth Meyers, Andrew Bird
Episode 79 Lauren Graham, Guy Fieri, MENEW
Episode 80 Renee Zellweger, Tony Dungy, Graham Nash sits in with the band
Episode 81 Mary Hicks, the Gaslight Anthem
Episode 82 Ben Roethlisberger, Steve Martin
Episode 83 Rod Blagojevich, Richard Jenkins
Episode 84 Joe Torre, Demetri Martin, Lyle Lovett and John Hiatt
Episode 85 Isla Fisher, extreme fisherman Matt Watson, Mark Olson and Gary Louris, a Top Ten List presented by Lil' Wayne
Episode 86 Dakota Fanning, Keith Alberstadt, Beirut
Episode 87 Naomi Watts, Danny McBride, 2009 Sports Illustrated Swimsuit Issue cover reveal
Episode 88 The crew of US Airways "Miracle On The Hudson" Flight 1549, Heartless Bastards
Episode 89 Joaquin Phoenix, Bar Refaeli, Anthony Hamilton
Episode 90 Chris Russo, the Jonas Brothers, Ashford & Simpson
Episode 91 Martha Stewart, Jake Johannsen, Matt Nathanson
Episode 92 Ellen Pompeo, Daytona 500 winner Matt Kenseth, Willie Nelson with Asleep at the Wheel
Episode 93 Bonnie Hunt, M. Ward
Episode 94 Donald Trump, Antony and the Johnsons
Episode 95 David Spade, Jeffrey Sachs, David Sanborn with Sam Moore
Episode 96 Barbara Walters, Mike Birbiglia, Shemekia Copeland
Episode 97 Katie Couric, U2
Episode 98 Felicity Huffman, Artie Lange, U2
Episode 99 Dr. Phil McGraw, U2
Episode 100 Jon Stewart, U2, a Top Ten List featuring 10 Team USA members from the World Baseball Classic
Episode 101 Jason Segel, Brian Kiley, U2
Episode 102 Russell Brand, Jack Hanna
Episode 103 Stupid Pet Tricks, Paul Rudd, Razorlight
Episode 104 Tom Brokaw, An Horse
Episode 105 Andy Samberg, Paul Teutul Sr., the Broadway cast of "West Side Story"
Episode 106 Will Ferrell, Cursive
Episode 107 Nicolas Cage, Rachel Maddow
Episode 108 Julia Roberts, Bell X1
Episode 109 Craig Ferguson, Ginnifer Goodwin, Modest Mouse
Episode 110 Billy Crystal, Kara DioGuardi, a Top Ten List presented by Owen Wilson
Episode 111 David Spade, Richard Zoglin, David Sanborn and Sam Moore
Episode 112 Hugh Laurie, Bloc Party
Episode 113 Mary Tyler Moore, Blake Lively, White Lies
Episode 114 Christina Applegate, Jim Gaffigan, Jesse Harris with Norah Jones
Episode 115 Seth Rogen, Tom Dreesen, Adele
Episode 116 Bill O'Reilly, Marianne Faithfull
Episode 117 Marg Helgenberger, Francisco Palacios, Ray LaMontagne
Episode 118 Michael J. Fox, the Fray
Episode 119 Denis Leary, Diana Krall
Episode 120 Zac Efron, Mike Golic and Mike Greenberg, A.C. Newman with Nicole Atkins
Episode 121 Kelly Ripa, Bill Scheft, Yeah Yeah Yeahs
Episode 122 Drew Barrymore, Jack McBrayer, Neko Case
Episode 123 Matthew Perry, Elisha Cuthbert, Rascal Flatts
Episode 124 Russell Crowe, Joe Wong
Episode 125 Jeff Goldblum, Jeff Dunham
Episode 126 Nathan Lane, Tinted Windows
Episode 127 Beyonce, Jim Parsons
Episode 128 Jamie Foxx, Lauren Conrad, the Dead
Episode 129 Michael Keaton, Lily Allen
Episode 130 Matthew Fox, Carol Leifer, the All-American Rejects, a Top Ten List presented by Matthew Stafford
Episode 131 Dolly Parton, Zachary Quinto
Episode 132 Jennifer Garner, Tesla Motors CEO Elon Musk, Manchester Orchestra
Episode 133 Regis Philbin, a performance by the Broadway cast of "Hair"
Episode 134 Kiefer Sutherland, Jim Norton, Bat for Lashes
Episode 135 Gordon Ramsay, Chris Pine, Keri Hilson with Kanye West
Episode 136 Liev Schreiber, Dr. Sanjay Gupta, Franz Ferdinand
Episode 137 Bruce Willis, Ben Harper & Relentless7
Episode 138 Norm MacDonald, a Top Ten List presented by Leonard Nimoy, Animal Collective
Episode 139 Matthew Broderick, Brian Regan, Chris Cornell
Episode 140 Tom Hanks, the Killers
Episode 141 Alec Baldwin, Maya Rudolph, Chrisette Michele
Episode 142 Robin Williams, Wynton Marsalis
Episode 143 Kid Scientists, Teri Hatcher, Rick Ross with Magazeen, a Top Ten List presented by Ron Howard
Episode 144 John Goodman, Tommy Tiernan, Mastodon
Episode 145 Ben Stiller, White Rabbits
Episode 146 Jane Fonda, Piedmont Bird Callers, Kenny Chesney
Episode 147 Stephen Colbert, General Motors Vice Chairman Bob Lutz, Grizzly Bear
Episode 148 Amy Sedaris, Ed Helms, Jean Redpath
Episode 149 Ricky Gervais, Green Day
Episode 150 Bill Cosby, Helio Castroneves, Melody Gardot
Episode 151 Jack Hanna, John Krasinski
Episode 152 Jessica Biel, Zach Galifianakis, Steve Earle
Episode 153 Elvis Costello, a Top Ten List presented by Neil Patrick Harris
Episode 154 Paris Hilton, Calvin Borel, Steven Wright
Episode 155 Howard Stern, Mos Def
Episode 156 Julia Roberts, Black Eyed Peas
Episode 157 Kathy Griffin, Stupid Human Tricks, Sonic Youth, an NBA Finals report by Phoenix Suns' Steve Nash
Episode 158 Denzel Washington, the Jonas Brothers, a Top Ten List with Regis Philbin
Episode 159 Sandra Bullock, Pete Correale, P.J. Harvey & John Parish
Episode 160 Jack Black, M.A. Sanjayan
Episode 161 Michelle Pfeiffer, Judah Friedlander, Ian McLagan & the Bump Band
Episode 162 Ryan Reynolds, Padma Lakshmi, the Eels
Episode 163 Danny DeVito, Bear Grylls, Phoenix
Episode 164 Jada Pinkett Smith, Michael Cera, the Sounds
Episode 165 Samuel L. Jackson, Emeril Lagasse, Iggy Pop & the Brighton Port Authority
Episode 166 Sandra Day O'Connor, MSTRKRFT with John Legend, a Top Ten List presented by Lucas Glover
Episode 167 Ray Romano, St. Vincent
Episode 168 Johnny Depp, Megan Fox
Episode 169 Martin Short, Regina Spektor
Episode 170 Serena Williams, Hayden Panettiere, Conor Oberst and the Mystic Valley Band
Episode 171 Sacha Baron Cohen, Joel McHale
Episode 172 Queen Latifah, Emma Watson
Episode 173 Daniel Radcliffe, Veronika Part, Levon Helm, a Top Ten List presented by Bruno
Episode 174 Rainn Wilson, Larry Miller, Maxwell
Episode 175 Jonah Hill, Gar Ryness, Kelly Clarkson
Episode 176 Edie Falco, Michael Showalter, Wilco with Feist
Episode 177 Paul McCartney, a Top Ten List presented by Bruce Willis
Episode 178 Anderson Cooper, Anna Paquin, Grizzly Bear
Episode 179 Tom Arnold, Metric, a Top Ten List presented by Dave's mom Dorothy
Episode 180 Katherine Heigl, Jeff Altman, Spinnerette
Episode 181 Kevin Spacey, Jesse James, the Flatlanders, a Top Ten List presented by Stewart Cink
Episode 182 Tracy Morgan, Leslie Mann, Diane Birch
Episode 183 Sean "Diddy" Combs, Vera Farmiga, Ginuwine with Missy Elliott
Episode 184 Amy Poehler, Nick Griffin, Judy Collins
Episode 185 Eric Bana, Dave Matthews Band, a Top Ten List presented by Chicago White Sox star Mark Buehrle
Episode 186 Katie Couric, Silversun Pickups
Episode 187 Amy Adams, Tom Dreesen, Elbow
Episode 188 Adam Sandler, Cage the Elephant
Episode 189 Regis Philbin, Ted Alexandro, Dave Matthews Band
Episode 190 Quentin Tarantino, Eric Ripert, Robert Cray
Episode 191 Donald Trump, Diane Kruger, Billy Currington, a Top Ten List presented by Britney Spears
Episode 192 Mike Myers, Ken Burns
Episode 193 Anna Wintour, Mark Teixeira
Episode 194 Renee Zellweger, Gary Mule Deer
Episode 195 Christina Applegate, Brendan Benson, Patton Oswalt
Episode 196 Anna Wintour, Mark Teixeira
Episode 197 Mary-Louise Parker, Eugene Levy, Jet
Episode 198 Anne Heche, Jim Parsons, Care Bears on Fire
Episode 199 Andy Roddick, Rachael Ray, Mutemath
Episode 200 Artie Lange, Todd Barry, Imogen Heap
Late Show with David Letterman - Season 16 Episode 23 : Bill Murray, Beck
Michael Bearden fills in for Paul; a man wanders onstage to get his copy of the Fun Facts book autographed; Bill Murray promotes City of Ember and conducts a town hall debate; Beck performed "Gamma Ray."
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